-
Vigabatrin (VGB) is an antiepileptic drug (AED) whose putative mechanism of action is to increase inhibitory tone in the brain by blocking the metabolism of gamma-amino butyric acid (GABA) by irreversibly binding to GABA transaminase.
-
Benign hyperckemia may be defined as serum elevation of creatine kinase (CK) in an asymptomatic patient or in a patient with nonspecific symptoms, including muscle pain, fatigue, cramps, stiffness, normal neurological examination, and normal or nondiagnostic electrodiagnostic (nerve conduction studies and electromyography) studies.
-
Taylor and associates report a case of Hashimoto encephalopathy in an adolescent girl with a 9-month history of what was initially diagnosed as chronic fatigue syndrome.
-
-
Although gemcitabine has been proven to be of value in the treatment of advanced pancreatic cancer, remission rates remain low and survival is measured in weeks to months. Swiss investigators report the results from a phase I/II study of combined gemcitabine/capecitabine treatment.
-
The standard of care for early lung cancer is surgery. However, in aged or frail patients, or in those whose pulmonary or cardiac status is compromised, radical surgery may be contraindicated.
-
-
Platinum-based adjuvant chemotherapy improved overall survival and recurrence-free survival at 5 years in this combined group of patients with early-stage ovarian cancer defined by the inclusion criteria of the ICON1 and ACTION trials.
-
Cardiac resynchronization reduces the mortality of progressive heart failure in patients with symptomatic left ventricular dysfunction and dyssynchrony.
-
In this study, a European consortium of investigators evaluated the ability of an automatic external cardioverter defibrillator (AECD) to detect and treat arrhythmias in the in-hospital setting.